Don't use front-page or dreamweaver. Those are for design jocks who could care less about quality of the overall web project – just how much it sparkles. Recommending front-page is like that of promoting comic sans usage for long continuous text. If I ran a professional web forum and someone promoted front-page I would ban them for being an incompetent fraud. Promoting things like front-page doesn't do anything but hurt both the industry and new comer to it. I know people are free to say what they want but expect those who are passionate about improving the quality of the web to call it out because front-page for web development is utter and complete crap. I would go far as to put Dreamweaver in that category but I won't…
You don't need a HTML5 framework. What you need to do is if not already familiar learn HTML and CSS. Notice I did not say HTML5, I said HTML. That is because HTML5 is not complete and will only get in the way of learning the basics which when understood can easily be transitioned to HTML5. Considering HTML5 is nothing more than a buzzword for additions and deprecations to HTML4 (draft standard).
What you *may need is a sever-side framework. There are frameworks out there of all kinds from simple to complex from CMSs to merely toolsets. It all depends on the server-side language you would learn, project requirements but *mostly preference. Considering learning any toolset is a huge undertaking. It isn't to practical to become a master of them all but pick one or two and master those.
That would be the semi-proper way to go about things. The proper but less than ideal building your own framework based on specific project requirements. The completely wrong way relying on tools like Dreamweaver, Front-page, Site-grinder, etc to make critical technical decisions for you which they suck at making.