I was introduced to e-readers using MobiPocket on an old Palm IV. Now, I have a B&N Nook. I love it. I love to read, and I'm usually reading 2 or 3 books at a time. I probably go through about 3 novels a week. The thing that I love about e-readers in general, is the ability to carry around 4000 books in one device. If I finish one book, I can just scroll over to the next one and keep reading.
To me the most important thing is the story. I don't care whether it's bound in soft Corinthian leather and printed on heavy linen paper. I realize that some people love the feel and romance of books, but I just don't get it. Is Ender's Game a better book if you read it in hardcover? Does Frodo keep the Ring if it's a battered old paperback?
Another plus with e-books is that I'm more apt to try new writers. Since I don't have the physical encumbrance of a book, I'm more likely to load something in my Nook and give it a try. Baen books has figured this part out already with their free online library. Not to mention the environmental concerns... E-books don't use paper, and they last forever.
Sorry for the rant. As to the OP's comments, I think price & format confusion are currently the biggest issues in the e-reader market. Do I want a Kindle or a Nook or a RocketReader or whatever Sony's got out? Pdf, .mobi, .lit, .html, .azw, .epub, .fb2, .pdb? And can I read all of my e-books on one reader? I felt safe going with the Nook, since it has a broad range of formats that it can use, plus I have apps that can convert between them, but it can be frustrating. And people don't want to spend $200 on a reader that can't read other formats.