The best way to do this is to draw it out by hand on a piece of paper. Once you do, you will have a bunch of boxes, or the "structure". Then you have to lay them out. All layout design is about boxes and how they relate to one another (with the browser being the biggest box). Some are next to eachother. Some are inside of each other. Some are above each other, etc. Start by googling "css box model".
You should try something like Lynda.com. If you want to spring for a copy of dreamweaver (or get it as a part of Adobe's Creative Cloud), Lynda has some great tutorials on getting started with Dreamweaver that can help you design this thing in a matter of a couple of days.
But overall, it is important to note that when you come to a forum like this, it really helps to have something to show the community so they can help you tweak it or redesign it. It also shows that you have put some work into it, as well.