Sorry, you're not going to have much success when dealing with pdf files.
It can be done, but isn't pretty.
Also check his out: http://www.artviper.net/website-tools/bumpbox-lightbox.php
It bills itself as "a lightbox clone with support for PDF", but I've no idea how effective it is.
Please report back if you get this working, as it would be interesting to find out how.
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