Well even if ports are in use you could change the ports easily. Thats not a major issue.
You need to go to xampp folder > apache > conf > httpd.conf
find the port Listen
You can change that to any port and then when you access local host you need to say localhost:XX so that it loads web from that port.
Similarly for 443 port you need to go to httpd-ssl.conf and change the listen port
Then restart apache and you should be ok.